40X-1000X Seidentopf Binocular Biological Microscope (N-PW300)

• Model NO.: N-PW300
• Type: Biological
• Mobility: Desktop
• Shape: Triangular Prism
• Principle: Optics
• Mechanical Stage: 140mm X 132mm
• Transport Package: Foam and Carton
• Origin: China

• Magnification: >1000X
• Number of Cylinder: Binoculars
• Stereoscopic Effect: Without Stereoscopic Effect
• Usage: Research
• Principle of Optics: Biological Microscope
• Trademark: ProWay
• Specification: CE
• HS Code: 9011800090

Advantage: 

Excellent image quality with infinitive optical system; 

Comfortable operating with ergonomic structure; 

Better illumination with sliding-in centerable condenser, convenient replacement with phase contrast and dark field condenser. 

Specification: 





Workshop: 





Digital Camera Eyepiece Recommending: 
Through below digital camera eyepiece, the Micro-Image could display
On computer immediately.  

Macitentan API And Intermediates

Macitentan is an orally available dual endothelin receptor (ETR) antagonist with potential antihypertensive and antineoplastic activity. Upon administration, macitentan and its metabolites block the binding of endothelin isoform 1 (ET-1) to type-A and type-B ETR on both the tumor cells and the endothelial cells in the tumor vasculature. This prevents ET-1 mediated signaling transduction which may decrease tumor cell proliferation, progression, and angiogenesis in tumor tissue. ET-1, a potent vasoconstrictor that plays an important role in inflammation and tissue repair, is, together with its receptors, overexpressed varyingly in many tumor cell types.

Macitentan is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH). Macitentan has been associated with a low rate of serum enzyme elevations during therapy, but has yet to be implicated in cases of clinically apparent acute liver injury.

Macitentan is a member of the class of sulfamides in which the two amino groups of sulfonamide are substituted by 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl and propyl groups. An orphan drug used for the treatment of pulmonary arterial hypertension. It has a role as an endothelin receptor antagonist, an antihypertensive agent and an orphan drug. It is an organobromine compound, a member of pyrimidines, an aromatic ether, a ring assembly and a member of sulfamides. It derives from an ethylene glycol and an ACT-132577.

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Macitentan API cas 441798-33-0,Macitentan Intermediate 146533-41-7,Macitentan Intermediate 706811-25-8,Macitentan Intermediate 147962-41-2 Manufacturers and Suppliers in China

 Shandong Haohong Biotechnology Co., Ltd. , https://www.haohongpharma.com